오이풀 추출물이 mutans streptococci의 성장과 hydroxyapatite beads에의 부착에 미치는 효과
Effects of crude Sanguisorba officinalis L. extract on the growth and the adherence to hydroxyapatite beads of mutans streptococci
손광진, 이순애, 이기돈, 김영삼, 유미경, 이광원,
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손광진 ( ) - 전북대학교 치과대학 예방치학교실
이순애 ( ) - 전북대학교 치과대학 예방치학교실
이기돈 ( ) - 전북대학교 치과대학 예방치학교실
김영삼 ( ) - 전북대학교 치과대학 예방치학교실
유미경 ( ) - 전북대학교 치과대학 예방치학교실
이광원 ( ) - 전북대학교 치과대학 예방치학교실
KMID : 0355420040280010097
Abstract
In this study, the crude Sanguisorba offrcinalis L. extract was examined for the effects on the growth and the adherence to hydroxyapatite beads by some mutans streptococci. The strains of mutans streptococci tested were S. mutans KCTC 3298, S. sobrinus KCTC 3307, S. cricetus KCTC 3292 and S. rattus KCTC 3294 strains. The results obtained were input SPSS/PC and analyzed by one-way ANOVA and Duncan test. The crude Sanguisorba officinalis L. extract inhibited the colony forming unit markedly at the concentrations of 0.25 mg/ml. The adherence to the saliva-coated hydroxyapatite beads of S. mutans KCTC 3298, S. sobrinus KCTC 3307, S. cricetus KCTC 3292 and S. mttus KCTC 3294 strains were inhibited by 24.3%,19.4%, 15.4%, and 8.6% in the crude Sanguisorba officinalis L. extract at the concentrations of 0.25 mg/ml (p < 0.05). The adherence to the saliva-coated hydroxyapatite beads of S. mutans KCTC 3298 and S. cricetus KCTC 3292 were inhibited 100% by the crude Sanguisorba officinalis L. extract at the concentrations of 2 mg/ml, and S sobfinus KCTC 3307 and S. rattus KCTC 3294 were inhibited 100% by the extract at the concentrations of 1 mg/ml (p < 0.05).
These results indicated that the crude Sanguisorba officinalis L. extract can be used as a possible anticariogenic agents.
키워드
hydroxyapatite;오이풀;우식성세균;항세균효과;antibacterial effect;mutans streptococci;Sanguisorba officinalis L
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